Publications

(2023) “Xeno Amino Acids: A Look into Biochemistry as We Do Not Know It” Brown, S.M.; Mayer-Bacon, C.; Freeland, S. Life, 13, 2281

(2023) “What Would an Alien Amino Acid Alphabet Look Like and Why?” Brown, S.M., Voráček, V., Freeland, S.J., Astrobiology, 23(5), 536-549

(2022) “Curation of Computational Chemical Libraries Demonstrated with Alpha-Amino Acids” Mayer-Bacon, C., Yirik, M.A. J Vis Exp
(182).

(2022) “A Closer Look at Non-random Patterns Within Chemistry Space for a Smaller, Earlier Amino Acid Alphabet.” Mayer-Bacon, C., Meringer, M., Havel, R., Aponte, J. C., & Freeland, S., Journal of Molecular Evolution, 1-17.

(2021) “A broader context for understanding amino acid alphabet optimality,” Mayer-Bacon C., S. J. Freeland S.J., Journal of Theoretical Biology, Vol. 520, 110661

(2021)  “Evolution as a Guide to Designing xeno Amino Acid Alphabets,” Mayer-Bacon C., Agboha N., Muscalli M. and Freeland S. International Journal of Molecular Sciences. 22(6), 2787;

(2021) “Rethinking abiogenesis Part 2: Life as a Simplification of the Nonliving Universe” Boring E., Isaac R. , S. Freeland., Perspectives on Science and Christian Faith Volume 73, pp. 100-113

(2020) “Rethinking Abiogenesis Part 1: Continuity of Life over Time” Boring E., Stump J.B., and Freeland S., Perspectives on Science and Christian Faith, Vol. 72(1): pp. 25-35

(2019)“Adaptive Properties of the Genetically Encoded Amino Acid Alphabet Are Inherited from Its Subsets.” Ilardo M, Bose R, Meringer M, Rasulev B, Grefenstette N, Stephenson J, Freeland S, Gillams RJ, Butch CJ, Cleaves HJ 2nd. Scientific Reports 9(1):12468

(2015)“Extraordinarily adaptive properties of the genetically encoded amino acids.” Ilardo M, Meringer M, Freeland S, Rasulev B, Cleaves HJ 2nd. Scientific Reports 5:9414

(2014) “Testing for adaptive signatures of amino acid alphabet evolution using chemistry space” M. A. Ilardo and S Freeland, Journal of Systems Chemistry, 5:1

(2013)“Beyond terrestrial biology: charting the chemical universe of α-amino acid structures.” Meringer M, Cleaves HJ 2nd, Freeland SJ. Journal of Chemical Information and Modeling. 53(11):2851-62

(2013) “Unearthing the root of amino acid similarity” Stephenson JD, Freeland SJ. Journal of Molecular Evolution 77(4):159-69

(2011)  “The Origins of Genetic Information” Freeland S. Perspectives on Science and Christian Faith, 63(4): 240-254

(2011) “Did evolution select a non-random “alphabet” of amino acids?” Freeland S. and Philip G.K., Astrobiology: 11: 235–240;

(2008) “A quantitative investigation of the chemical space surrounding amino acid alphabet formation.” Lu Y and Freeland SJ, Journal of Theoretical Biology 250:349-61.

Peer Reviewed book Chapters.

(2010)“Terrestrial” Amino Acids and their Evolution”  S.J. Freeland, Chapter 2 of Amino Acids, Peptides and Proteins in Organic Chemistry, Volume 1 – Origins and Synthesis of Amino Acids, eds. A.B. Hughes, Wiley-VCH, Weinheim.

(2008)“Could an intelligent alien predict earth’s biochemistry?” S.J. Freeland, Chapter 14 of Fitness of the Cosmos for Life, eds. J. Barrow, S. Conway-Morris and S. J. Freeland, Cambridge University Press. Cambridge UK.

(2021) Chapter 3: “One in a million? The chemistry of life in the universe” S. J. Freeland and Ruth Bancewicz in Wonder of the Living World, ed. R. M. Bancewicz, Lion Publishing, Oxford.

(2020) Extending CoNavigator into a Collaborative Digital Space, Don Engel, Stephen Freeland, Lee Boot, Mark Jarzynski, Katrine Lindvig, Line Hillersdal, David Earle, Companion of the 2020 ACM International Conference on Supporting Group Work

(2019) Origins of Life: The Questions Are Big, and The Answers Complex, Stephen Freeland, BioLogos web resource: https://biologos.org/articles/origins-of-life-the-questions-are-big-and-the-answers-complex

(2017) “Creative Assessment of the 2016 Origins Ideas Lab: A Fresh Approach to Generating Scientific Research” (UMBC Commons)

(2011) “Language Evolution in Humans and Ancient Microbes: What can human language acquisition tell us about the origin of genetic information?” Ilardo M and Freeland S.J. PERILUS Symposium on Language Acquisition and Language Evolution, The Royal Swedish Academy of Sciences and Stockholm University, pp 63-76.

(2004) “Evolution Encoded” S.J. Freeland and L. Hurst, Scientific American, 290:84-91.